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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGO2 All Species: 16.06
Human Site: S26 Identified Species: 29.44
UniProt: Q9BRQ0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ0 NP_612157.1 406 41244 S26 A P P P A P P S T G R K Q G K
Chimpanzee Pan troglodytes XP_525221 567 57276 S188 A P P P A P P S T G R K Q G K
Rhesus Macaque Macaca mulatta XP_001114666 405 41081 S26 A P P P A P P S T G R K Q G K
Dog Lupus familis XP_547562 405 41099 G26 A P P P A P P G T G R K Q G K
Cat Felis silvestris
Mouse Mus musculus Q9D0P5 417 45071 S20 K R V R G G D S G L D G L G G
Rat Rattus norvegicus NP_001099917 405 41066 S26 A P P P A P P S T G R K Q G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514326 407 43303 S22 G P G V Q L G S P D K K K R K
Chicken Gallus gallus NP_001019862 418 44852 G20 K R S R G G D G G L D G L G G
Frog Xenopus laevis NP_001082328 389 41400 K19 S L P G R R A K T G M Q M K S
Zebra Danio Brachydanio rerio NP_001028283 571 56263 G132 T G P H H P L G F G G M P G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9W8 815 80474 N66 A A A A A A A N S M Q Q Q Q A
Honey Bee Apis mellifera XP_394285 396 41911 M44 M P H N M G S M S P M G N S P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791313 224 24117
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.2 98.5 96.8 N.A. 36.4 96.3 N.A. 37.3 33.9 67.7 33.6 N.A. 21.3 23.3 N.A. 24.6
Protein Similarity: 100 71.2 98.7 97 N.A. 48.2 97 N.A. 48.1 44.2 74.8 39.5 N.A. 27.9 34.7 N.A. 35.4
P-Site Identity: 100 100 100 93.3 N.A. 13.3 100 N.A. 26.6 6.6 20 26.6 N.A. 20 6.6 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 100 N.A. 40 6.6 33.3 26.6 N.A. 46.6 13.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 8 8 8 47 8 16 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 8 16 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 8 8 8 8 16 24 8 24 16 54 8 24 0 62 16 % G
% His: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 8 0 0 8 47 8 8 47 % K
% Leu: 0 8 0 0 0 8 8 0 0 16 0 0 16 0 0 % L
% Met: 8 0 0 0 8 0 0 8 0 8 16 8 8 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 0 8 0 0 % N
% Pro: 0 54 54 39 0 47 39 0 8 8 0 0 8 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 8 16 47 8 0 % Q
% Arg: 0 16 0 16 8 8 0 0 0 0 39 0 0 8 0 % R
% Ser: 8 0 8 0 0 0 8 47 16 0 0 0 0 8 8 % S
% Thr: 8 0 0 0 0 0 0 0 47 0 0 0 0 0 0 % T
% Val: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _